Carlo Gregorio Verdone already as a child has the opportunity to approach the world of cinema thanks to his father, Mario Verdone, famous film historian, university professor, scholar of historical avant-garde, long manager of the Experimental Center of Cinematography and close friend of personalities among the most successful of the time, such as Pier Paolo Pasolini, Federico Fellini, Alessandro Blasetti, Franco Zeffirelli, Michelangelo Antonioni, Roberto Rossellini, Vittorio De Sica.
In 1971, with a video camera sold by Isabella Rossellini, he made a short film entitled "Solar Poetry" (lasting about 20 minutes), influenced by the sixty-eighth and psychedelic culture of the time, and by the music of Pink Floyd and Grateful Dead.
In 1972 Carlo enrolled in the Experimental Center of Cinematography and, in 1974, he graduated in film directing, under the presidency of Roberto Rossellini. The diploma essay is titled "Anjuta", inspired by a short story by Cecov, with the participation of Lino Capolicchio (at the time already an established actor), Christian De Sica, Giovannella Grifeo and Livia Azzariti.
In 1974, in addition to working on the set of the film as a second assistant director, he appeared in Franco Rossetti's "That movement that I like so much", a classic Italian erotic comedy (very popular in the 70s) with the inevitable Renzo Montagnani; in addition, Carlo does some other work in assisting direction with Zeffirelli and takes care of the direction of some didactic documentaries for the Prime Minister.
A fundamental meeting for Carlo's career is that with Sergio Leone, from which, in addition to the debut film "Un Sacco Bello" and the following "Bianco, Rosso & Verdone", the collaboration with the screenwriters Leo Benvenuti and Piero De Bernardi.
During his career Carlo worked with various producers, from Mario and Vittorio Cecchi Gori, to Warner Bros, to Medusa, to Titanus, before signing the current contract with Aurelio and Luigi De Laurentiis.
Among the known characteristics of Carlo there is that of having directed a considerable number of Italian actresses, enhancing their potential at the highest levels. Almost all of them have won prestigious awards in their films, such as the David di Donatello and the Nastri d’Argento.